Ajax vs Inter Milan Prediction & Expert Tips

Ajax vs Inter Milan Match Preview

Ajax host Inter Milan in a highly anticipated Champions League encounter, with both clubs eager to stamp their authority early in the group stage. The Dutch giants have been steady domestically, building confidence with consistent results, while Inter arrive from Serie A with mixed fortunes, though still carrying plenty of firepower. With history favouring the Italians in past meetings, this clash promises intensity and goals.

Ajax enter this fixture on the back of an encouraging run of results at home. Wins over PEC Zwolle (3-1), Heracles (2-0), and Telstar (2-0) underline their strength at Johan Cruyff Arena, where they’ve conceded just once in their last three outings.

However, away from home their weaknesses were exposed in a 2-2 draw at GA Eagles and a 1-1 against Volendam. Ajax remain a side that thrives in front of their supporters, but questions linger about their ability to contain elite-level opposition when pressured defensively.

Inter Milan, meanwhile, have endured a rollercoaster start to their campaign. A crushing 5-0 win over Torino showed their ceiling, but back-to-back defeats to Udinese (1-2) and Juventus (3-4) highlighted defensive lapses and inconsistency.

Lautaro Martínez remains their talisman, already carrying the scoring burden with his sharp finishing and relentless movement. If Inter are to prevail in Amsterdam, he will be the one most likely to break Ajax’s defensive structure.

Head-to-head history also tilts toward Inter. These sides last met in the 2005/06 Champions League Round of 16, where Inter advanced 3-2 on aggregate after a 1-0 win in Milan and a 2-2 draw in Amsterdam.

Going further back, Inter also defeated Ajax 2-1 in the 2002/03 group stage, meaning the Nerazzurri remain unbeaten in their last three clashes with the Dutch club.

Ajax vs Inter Milan Prediction

This matchup has the look of a competitive, end-to-end affair. Ajax’s home form suggests they will find the net, but Inter’s superior attacking talent and history in this fixture give them the advantage.

The best angle lies in Inter to Win at 1.85 odds, while Both Teams to Score & Over 2.5 goals (2.00 odds) add value given Ajax’s ability at home.

Lautaro Martínez to score anytime (2.25 odds) is a natural pick, and for those chasing bigger value, the 2-1 Correct Score for Inter at 8.50 odds fits the likely script.

Marco Marin- September 15, 2025

Ajax vs Inter Milan Betting Tips

Inter Milan to Win

OK

1.85 Odds

Both teams to Score & Over 2.5 goals

OK

2.00 Odds

Lautaro Martinez to score anytime

OK

2.25 Odds

Inter 2-1

OK

8.50 Odds